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Anglický jazyk
A Master Regulator of Oxidative StressThe Transcription Factor Nrf2
Autor: Jose Antonio Morales-Gonzalez
Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens... Viac o knihe
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O knihe
Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.
- Vydavateľstvo: IntechOpen
- Rok vydania: 2016
- Formát: Hardback
- Rozmer: 266 x 185 mm
- Jazyk: Anglický jazyk
- ISBN: 9789535128373
