Anti-cancer and Renal Protection by C-Type Natriuretic Peptide

Anglický jazyk

Anti-cancer and Renal Protection by C-Type Natriuretic Peptide

Vydavateľstvo: Storyfire Ltd
Rok vydania: 2023
Formát: Paperback
Rozmer: 229 x 152 mm
Jazyk: Anglický jazyk
ISBN: 9781805270959

1 kus skladom u vydavateľa Posielame do 7-10 dní

13.16 €

bežná cena: 14.95 €

O knihe

The C-Type Natriuretic Peptide (CNP) is a peptide hormone that has been shown to possess anti-cancer and renal protective properties. This experimental study on Swiss albino mice aims to investigate the potential of CNP as a therapeutic agent for cancer therapy and renal protection. In vitro and in vivo experiments were conducted to evaluate the effect of CNP on tumor growth, cell signaling, apoptosis, proliferation, and chemotherapy-induced nephrotoxicity. Biochemical studies were also conducted to assess the biomarkers associated with cancer and renal damage, such as oxidative stress, inflammation, and angiogenesis. The results of the study revealed that CNP treatment led to a significant reduction in tumor growth and nephrotoxicity. CNP was found to induce apoptosis and inhibit proliferation of cancer cells, while also protecting the renal function against chemotherapy-induced damage. The mechanism of action of CNP involves activation of cyclic GMP and nitric oxide pathways, as well as modulation of cellular pathways and gene expression. Additionally, CNP was found to possess antioxidant properties and to modulate the immune response, which contributed to its anti-cancer and renal protective effects. Overall, the findings of this study suggest that CNP has the potential to be a promising therapeutic agent for cancer therapy and renal protection. Future clinical trials and drug development studies should be conducted to further investigate the efficacy and safety of CNP in cancer prevention and treatment.