• Anglický jazyk

Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C-H Bonds

Autor: Stacey L. McDonald

This thesis reports the latest developments in the direct amination of various C-H bonds using an H-Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized... Viac o knihe

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O knihe

This thesis reports the latest developments in the direct amination of various C-H bonds using an H-Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines.


The material outlined in this book shows how McDonald achieved C-H zincation using strong, non-nucleophilic zinc bases and subsequent electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines as the electrophilic nitrogen source.


McDonald's findings are of relevance to medicinal chemistry, drug discovery and materials science. Her thesis is a source of inspiration for scientists entering the field and students beginning their PhD in a related area.

  • Vydavateľstvo: Springer International Publishing
  • Rok vydania: 2016
  • Formát: Hardback
  • Rozmer: 241 x 160 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783319388779

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