• Anglický jazyk

D-Dopachrome Tautomerase (D-DT)

Autor: Wibke Karin Schulte

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine and a pivotal regulator of the immune response implicated in the pathogenesis of various acute and chronic inflammatory diseases. In 1993, D-dopachrome tautomerase (D-DT) was discovered... Viac o knihe

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O knihe

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine and a pivotal regulator of the immune response implicated in the pathogenesis of various acute and chronic inflammatory diseases. In 1993, D-dopachrome tautomerase (D-DT) was discovered during an investigation of melanogenesis. The tertiary structure of D-DT is remarkably similar to MIF, identifying D-DT as the only known eukaryotic MIF homologue discovered to date. Despite D-DT's intriguing similarities to the very well studied MIF, there have been very few reports on the biological functions and mechanisms of action of D-DT. This dissertation aimed at the functional characterization of D-DT in biological and pathophysiologic conditions.

  • Vydavateľstvo: Südwestdeutscher Verlag für Hochschulschriften
  • Rok vydania: 2012
  • Formát: Paperback
  • Rozmer: 220 x 150 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783838131610

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