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Anglický jazyk
Dendritic cells for the treatment of autoimmune disease
Autor: Dae-Seog Lim
A number of autoimmune disease models have been used to examine the anti-inflammatory and immunosuppressive effects of tolerogenic dendritic cells (tDCs). The aim of the present study was to investigate whether rosiglitazone-mediated DC (Rosi-DC) therapy... Viac o knihe
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O knihe
A number of autoimmune disease models have been used to examine the anti-inflammatory and immunosuppressive effects of tolerogenic dendritic cells (tDCs). The aim of the present study was to investigate whether rosiglitazone-mediated DC (Rosi-DC) therapy suppressed arthritis in a collagen-induced arthritis (CIA) mouse model. The results presented herein show that type II collagen-pulsed Rosi-DCs ameliorate the inflammation associated with CIA via the induction of Treg cell population. These results suggest that rosiglitazone-mediated DCs hold promise as a novel therapeutic strategy for RA.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2016
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783659954856
