• Anglický jazyk

Expression of p53, Cyclin-D1 & EGFR in oral squamous cell carcinoma

Autor: Seema Gupta

Oral cancer pathogenesis is a complex process involving genetic alteration during multistep carcinogenesis, growth regulation, apoptosis, immortalization, angiogenesis, invasion and metastasis. Molecular markers such as p53, Cyclin-D1 and EGFR regulate cell... Viac o knihe

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O knihe

Oral cancer pathogenesis is a complex process involving genetic alteration during multistep carcinogenesis, growth regulation, apoptosis, immortalization, angiogenesis, invasion and metastasis. Molecular markers such as p53, Cyclin-D1 and EGFR regulate cell cycle and play important role in tumor progression and development. The present study evaluates the expressions of these molecular markers & its prognostic significance with treatment response in oral cancer patients undergoing chemoradiation. The strong positive expressions of p53, Cyclin-D1 and EGFR showed significantly lower survival as compared to negative or moderate positive expressions. Hence, expression of p53, Cyclin-D1 and EGFR may serve as a prognostic marker in oral cancer patients.

  • Vydavateľstvo: LAP LAMBERT Academic Publishing
  • Rok vydania: 2015
  • Formát: Paperback
  • Rozmer: 220 x 150 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783659672910

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