Anglický jazyk

Formulating Poorly Water Soluble Drugs

Vydavateľstvo: Springer International Publishing
Rok vydania: 2023
Formát: Paperback
Rozmer: 254 x 178 mm
Jazyk: Anglický jazyk
ISBN: 9783030887216

Na objednávku

222.63 €

bežná cena: 252.99 €

O knihe

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist¿s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound¿s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.