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Anglický jazyk
Gls Analysis for Identification the Right Ventricular Disfunction
Autor: Adina Glodeanu
Background: This study was designed to assess right ventricular (RV) systolic function in cancer patients. Methods and Results: Left ventricle (LV) and free-wall RV longitudinal strain were analysed prior and after 6 months of treatment (at 68 patients),... Viac o knihe
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O knihe
Background: This study was designed to assess right ventricular (RV) systolic function in cancer patients. Methods and Results: Left ventricle (LV) and free-wall RV longitudinal strain were analysed prior and after 6 months of treatment (at 68 patients), using a vendor-independent software, together with left ventricular ejection fraction (LVEF), tricuspid annulus plane systolic excursion and RV fractional area change. Cancer therapy-related cardiac dysfunction was defined as a LVEF drop of >10% to <53%. Both LVEF fraction (59±7% vs. 55±8%, p<0.0001) and LV longitudinal strain (¿19.7±2.5% vs. ¿17.1±2.6%, p<0.0001) were reduced.Cancer therapy-related cardiac dysfunction was detected in 20 patients (29%). In 15 out of these 20 patients (75%), a concomitant relative reduction in free-wall RV longitudinal strain magnitude by 17±7% was detected. A relative drop of RV longitudinal strain >17% had a sensitivity of 55% and a specificity of 70% to identify patients with cancer treatment. Conclusions: GLS analysis allows the identification of subclinical RV dysfunction appearing in the course of cancer treatment when conventional indices of RV dysfunction function are unaffected.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2022
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9786205490761
