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Anglický jazyk
Hepatitis C Virus NS3, NS5A and NS5B Proteins as Drug Targets
Autor: Mazhar Iqbal
Hepatitis C virus (HCV) infects ~ 3% of world population with significant mortalities in developing countries. If HCV disease goes untreated, it can lead to cirrhosis, hepatocellular carcinoma and ultimately death of the patient. Currently in Pakistan, about... Viac o knihe
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O knihe
Hepatitis C virus (HCV) infects ~ 3% of world population with significant mortalities in developing countries. If HCV disease goes untreated, it can lead to cirrhosis, hepatocellular carcinoma and ultimately death of the patient. Currently in Pakistan, about 5 to 10% of population is infected with HCV. This book provides useful informations about diagnostic, prevalence and drug discovery initiative against HCV genotype-3a (HCV-3a), the most prevalent genotype in developing world, particularly in South Asia including Pakistan. Drug discovery imitative is pursued by exploring the expression, purification and characterization of HCV-3a proteins such as NS3, NS5A and N5B, which are the targets of antiviral drugs. The newly developed direct acting antiviral drugs are less effective against HCV-3a as compared to genotype-1, therefore , studies describe in this book will help the relevant scientific professionals in designing better strategies to develop potent drugs against HCV-3a. From both, pharmaceutical market or human life saving point of views, there is a huge potential to develop cost effective and safer drugs to treat life-threatening disease caused by HCV.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2014
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783659634703
