• Anglický jazyk

Pharmacogenomic Effect on Biopharmaceutics of Anti-Tubercular Therapy

Autor: Swati Modgil

The first line anti-tuberculosis drugs are known to cause dose related adverse drug reactions like peripheral neuritis and hepatotoxicity. The risk of getting peripheral neuritis have been avoided through a concomitant administration of pyridoxine; while... Viac o knihe

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O knihe

The first line anti-tuberculosis drugs are known to cause dose related adverse drug reactions like peripheral neuritis and hepatotoxicity. The risk of getting peripheral neuritis have been avoided through a concomitant administration of pyridoxine; while hepatotoxicity remains to be a major adverse effect of anti- tuberculosis therapy. Research findings state reduction in the incidence of hepatotoxicity by exploring a potential link between biopharmaceutical pattern of anti-tuberculosis drugs and genetic polymorphism of the enzymes metabolizing them. Reportedly a significant correlation has been found by pooling the data through a meta-analysis.

  • Vydavateľstvo: LAP LAMBERT Academic Publishing
  • Rok vydania: 2022
  • Formát: Paperback
  • Rozmer: 220 x 150 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783330029347

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