-
Anglický jazyk
Polymorphisms in some genes associated with type 1 diabetes mellitus
Autor: Ali Salim Al-Shehmany
Type 1 diabetes (T1DM) is an autoimmune disease characterized by immune destruction of insulin-producing pancreatic ß cells. This leads to dysfunctional regulation of blood glucose levels in T1DM patients. The destruction of ß -cells of Langerhans islets... Viac o knihe
Na objednávku
36.99 €
bežná cena: 41.10 €
O knihe
Type 1 diabetes (T1DM) is an autoimmune disease characterized by immune destruction of insulin-producing pancreatic ß cells. This leads to dysfunctional regulation of blood glucose levels in T1DM patients. The destruction of ß -cells of Langerhans islets is caused by infiltration of dendritic cells, macrophages and T lymphocytes. Normally, genetic susceptibility (association) studies depend on assessing the role of genotype markers (typically SNPs) in the susceptibility to the disease of interest in a case- control or family based sample. Many genes associated with type 1 diabetes mellitus, CTLA-4, PTPN22, IL-10, IL-18, VIT-D receptor are one of the common confirmed T1DM susceptibility genes
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2015
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783659756375
