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Anglický jazyk
Pyrazolopyrimidine derivatives as cyclin-dependant kinase inhibitors
Autor: Phoebe F. Lamie
This book contains both review and synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as cycline dependent kinase inhibitors (CDKIs). Moreover, cytotoxic activity for the newly synthesized compounds were evaluated, specially on breast cancer cell line... Viac o knihe
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O knihe
This book contains both review and synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as cycline dependent kinase inhibitors (CDKIs). Moreover, cytotoxic activity for the newly synthesized compounds were evaluated, specially on breast cancer cell line (MCF-7). The results obtained were compared with methotrexate as a reference drug. Docking study and molecular modeling were also done using MOE program. I hope this work to be helpful and a starting point for much more new compounds with better activity to help in treatment of such a big terrible disease like cancer. Author: Phoebe F. Lamie
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2016
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783659792991
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