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Anglický jazyk
Statistical Issues in the Design and Analysis of Clinical Trials
Autor: Yanning Liu
Chapters 1-4 concern statistical methods in designing and analyzing data for survival clinical trials, and predicting trial duration. Chapters 5-7 concern statistical methods in clinical trials with sequential parallel designs, which have been proposed for... Viac o knihe
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O knihe
Chapters 1-4 concern statistical methods in designing and analyzing data for survival clinical trials, and predicting trial duration. Chapters 5-7 concern statistical methods in clinical trials with sequential parallel designs, which have been proposed for trials with high placebo response rates which can lead to a higher failure rate in drug development. Utilizing Box and Muller (1958), one of the most popular methods of generating standard normal random variable using two independent uniform (0, 1) deviates, a new method is proposed in Chapter 8 to combine two p-values from two disjoint samples for designing a trial with two stages.
- Vydavateľstvo: SPS
- Rok vydania: 2017
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783659845543
