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Anglický jazyk
Synthesis of N-aryl Pyrazoles via Chan-Lam Coupling
Autor: Kalpesh Vilapara
An efficient protocol to synthesized a small library of N-aryl pyrazoles via C-N bond Chan-Lam coupling reaction using diverse boronicacids at room temperature using Cu(OAc)2/TEA as a catalytic system without utilization of any ligand or additive and exposed... Viac o knihe
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O knihe
An efficient protocol to synthesized a small library of N-aryl pyrazoles via C-N bond Chan-Lam coupling reaction using diverse boronicacids at room temperature using Cu(OAc)2/TEA as a catalytic system without utilization of any ligand or additive and exposed to air to afford moderate to excellent yield. The characterizations of newly synthesized compounds were confirmed by FTIR, MS, 1H NMR, 13C NMR, and elemental analysis. All the synthesized compounds were assayed for their antibacterial activity against Staphylococcus aureus MTCC-96, Escherichia coli MTCC-443, B. subtilis MTCC-441, S. typhi MTCC-98, and antifungal activity against Aspergillus niger MTCC-282 and Aspergillus clavatus MTCC-1323 at different concentration and compared with standards drugs. The minimum inhibition concentration (MIC) of the compounds was studied by micro broth dilution method.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2019
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9786200255488
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