• Anglický jazyk

Anticonvulsant activity of pentazocine and its probable mechanism

Autor: Praveen Panchaksharimath

Pentazocine, which is known to act as an agonist at kappa opioid receptors and a weak antagonist or a partial agonist at mu receptors has shown significant anticonvulsant activity in MES test and abolition of this anticonvulsant activity by high dose but... Viac o knihe

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O knihe

Pentazocine, which is known to act as an agonist at kappa opioid receptors and a weak antagonist or a partial agonist at mu receptors has shown significant anticonvulsant activity in MES test and abolition of this anticonvulsant activity by high dose but not by low dose of Naloxone. The present study was designed to compare the anticonvulsant effect of Pentazocine with standard Sodium Valproate in albino rats. An attempt was also made to determine the possible opioid receptor mechanism involved.

  • Vydavateľstvo: LAP LAMBERT Academic Publishing
  • Rok vydania: 2012
  • Formát: Paperback
  • Rozmer: 220 x 150 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783848493692

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