-
Anglický jazyk
Developmental abnormalities associated with the hypopigmented retina
Autor: Marc Tibber
The albino visual system is characterised by a range of abnormalities including a severe rod deficit, an underdevelopment of the central retina and a misprojection of a portion of the temporal ganglion cells. During development of the retina levels of... Viac o knihe
Na objednávku, dodanie 2-4 týždne
73.17 €
bežná cena: 81.30 €
O knihe
The albino visual system is characterised by a range of abnormalities including a severe rod deficit, an underdevelopment of the central retina and a misprojection of a portion of the temporal ganglion cells. During development of the retina levels of proliferation and apoptosis are elevated, and the maturational gradient is delayed. During my PhD I systematically characterised the nature of these developmental abnormalities and examined the effects of L-DOPA (a precursor in melanin/dopamine synthesis pathways that is thought to be depleted in the albino retina) on patterns of cell division. The findings were consistent with a model in which reduced levels of L-DOPA in the albino retina lead to spatiotemporal defects in patterns of cell division, potentially as a result of secondary consequences on concentrations of retinal dopamine.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2011
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783844310344
