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Anglický jazyk
Pictet-Spengler Reaction to Indole Based Alkaloids
Autor: Kaushik Chanda
Indole based alkaloids are well known in the literature for their diverse biological properties. Polysubstituted optically active tetrahydro-ß-carboline derivatives functionalized on C-1 position are the common structural motif in most of the indole based... Viac o knihe
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O knihe
Indole based alkaloids are well known in the literature for their diverse biological properties. Polysubstituted optically active tetrahydro-ß-carboline derivatives functionalized on C-1 position are the common structural motif in most of the indole based alkaloids as well as highly marketed drugs. The stereoselective Pictet-Spengler reaction is one of the currently most important synthetic techniques used for the preparation of these privileged tetrahydro-ß-carboline scaffolds. To date there are numerous research reports that have been published on the synthesis of the tetrahydro-ß-carboline scaffold both on solid phase as well as in solution phase. Moreover rapid growth has been observed for the enantioselective synthesis of tetrahydro-ß-carboline scaffold using chiral organocatalysts. In this book, efforts have been taken to shed light on the latest information available on different strategies to synthesize tetrahydro-ß-carboline both on solid phase and in solution phase during the last 20 years.
- Vydavateľstvo: LAP LAMBERT Academic Publishing
- Rok vydania: 2017
- Formát: Paperback
- Rozmer: 220 x 150 mm
- Jazyk: Anglický jazyk
- ISBN: 9783330063112
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