• Anglický jazyk

Synthesis and characterization of Triazolo[4,3-c]pyrimidine library

Autor: Kalpesh Vilapara

A novel [1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide libraries were synthesized via oxidative cyclization of hydrazono-1,6-dihydropyrimidine-5-carboxamide intermediates by the application of Iodobenzenediacetate as a sole cyclizating agent. Here, we report... Viac o knihe

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O knihe

A novel [1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide libraries were synthesized via oxidative cyclization of hydrazono-1,6-dihydropyrimidine-5-carboxamide intermediates by the application of Iodobenzenediacetate as a sole cyclizating agent. Here, we report one pot sequential strategy to generate corresponding triazolopyrimidines by condensation of preprepared a-acylketene dithioacetals and arylamidines. Moreover, this process describes the application of presynthesized arylamidines which omits the transition metal catalyzed Suzuki-Miyaura cross coupling reaction hence signify the atom- and step-economic methodology.

  • Vydavateľstvo: LAP LAMBERT Academic Publishing
  • Rok vydania: 2019
  • Formát: Paperback
  • Rozmer: 220 x 150 mm
  • Jazyk: Anglický jazyk
  • ISBN: 9783659639852

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